GHK-Cu is a copper peptide studied for skin regeneration and collagen production.

Axiolabs

GHK-CU 50 mg

Manufacturer: Axiolabs
Pharmaceutical name: GHK-CU
Pack: vial (50mg per vial)
⚠️ Provided in a lyophilized powder for stability

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Description
Dosage Chart
Reconstitution Calculator
Mixing & Storage
Reviews

GHK-Cu 50 mg by Axiolabs - Skin Rejuvenation & Anti-Aging Copper Peptide

GHK-Cu (Copper Peptide) is a naturally occurring tripeptide complex consisting of glycine, histidine, and lysine bound to copper ions. It is widely researched for its role in skin regeneration, collagen synthesis, and anti-aging processes. Due to its unique ability to influence multiple pathways involved in tissue repair and skin health, GHK-Cu has become one of the most studied peptides in cosmetic and regenerative research.

As the skin ages, collagen production declines, leading to wrinkles, reduced elasticity, and slower repair. GHK-Cu has been investigated for its potential to support these processes by stimulating collagen formation and improving overall skin structure.

Important medical note: GHK-Cu is used in various cosmetic and research applications, but higher-dose peptide use should be supervised by a qualified professional where applicable.

How GHK-Cu Supports Skin Rejuvenation

GHK-Cu interacts with multiple biological pathways related to skin repair and regeneration. It has been studied for its ability to activate genes associated with tissue remodeling and healing.

Key mechanisms include:
• Stimulation of collagen and elastin production
• Promotion of skin cell regeneration
• Support for extracellular matrix remodeling
• Enhancement of wound healing processes

These mechanisms contribute to improved skin texture, elasticity, and overall appearance in research models.

Anti-Aging & Collagen Production

Collagen is the structural protein responsible for maintaining skin firmness and elasticity. With age, collagen levels decrease, leading to visible signs of aging.

GHK-Cu has been associated with:
• Increased collagen synthesis
• Reduction in fine lines and wrinkles
• Improved skin thickness and density
• Enhanced firmness and elasticity

Because of these properties, it is frequently included in discussions around anti-aging strategies and skin rejuvenation protocols.

Skin Repair & Regeneration

Beyond aesthetics, GHK-Cu has been studied for its role in wound healing and tissue repair. It may help accelerate skin recovery by promoting cellular turnover and supporting tissue regeneration.

Research observations include:
• Faster healing of minor skin damage
• Improved recovery from environmental stress
• Support for healthy skin barrier function

These regenerative effects make it relevant not only in cosmetic research but also in broader tissue repair discussions.

Comparison with Other Regenerative Compounds

GHK-Cu is often compared with peptides such as BPC 157 and TB-500.

While BPC 157 is associated with localized tissue repair and TB-500 with systemic recovery, GHK-Cu is primarily focused on skin regeneration and collagen remodeling. These differences highlight its unique position in aesthetic and regenerative research.

Comparison Table

Compound	Primary Role	Target Area	Main Benefit
GHK-Cu	Skin regeneration	Skin & connective tissue	Collagen production
BPC 157	Localized repair	Injury sites	Tissue healing
TB-500	Systemic recovery	Whole body	Full-body repair

Frequently Asked Questions

1) What is GHK-Cu?

GHK-Cu is a copper-binding peptide studied for its role in skin regeneration and collagen production.

2) Does GHK-Cu reduce wrinkles?

Research suggests it may support collagen synthesis and improve skin elasticity, which can reduce visible signs of aging.

3) How does GHK-Cu work?

It activates genes involved in tissue repair and supports extracellular matrix remodeling.

4) Is GHK-Cu used for skin repair?

Yes. It is widely studied for wound healing and skin regeneration processes.

5) Is GHK-Cu approved for medical use?

It is used in cosmetic applications, but broader uses may be considered investigational.

Approach	Amount	How often	Cycle	Best suited for
Research and clinician-guided ranges
Cautious start	0.5–1 mg	Once a day	Set on/off periods	First-time users, introduced slowly
Standard step-up	1 mg → 2 mg	Once a day	30 days on, 30 days off	Skin quality and healthy aging
Steady daily	1–2 mg	Once a day	Set on/off periods	Returning users who want a consistent dose
Higher intensity	2–3 mg	Once a day	Short, set cycle	Tissue and connective-tissue repair
Standard 30-day step-up schedule
Days	Daily dose	Stage
1–15	1 mg once a day	Active, lower dose
16–30	2 mg once a day	Active, increased dose
31–60	Rest period	Break to reassess
Key facts
What it is	A copper-binding tripeptide (glycyl-L-histidyl-L-lysine) linked to skin renewal, collagen support, and tissue remodeling
Usual route	Injection under the skin (subcutaneous), once a day
Typical cycle	30 days on, 30 days off, so the provider can reassess before continuing
Dosing approach	It works as a signaling peptide because of its copper component, so a higher dose is not automatically better
Often paired with	BPC-157 and TB-500 in tissue-repair discussions
Possible side effects	Reactions at the injection spot, sensitivity to copper, tiredness
Do not use if	Pregnant, breastfeeding, with Wilson's disease or another copper storage disorder, or without clinician supervision
Disclaimer	Figures are math conversions only; they do not confirm product quality, safety, or medical suitability

Reconstitution calculator
Find out how much bacteriostatic water to add and how many units to draw on your syringe for your GHK-Cu dose.
Peptide in the vial	mg
Bacteriostatic water	mL
Dose you want	mg
Syringe

Results
Choose your values and press Calculate.
Concentration	—
Amount to draw	—
Units to draw	—
Doses in the vial	—
How the math works
1. Find the concentration	Divide the peptide in the vial by the water added. For example, 50 mg ÷ 2 mL = 25 mg/mL
2. Work out the volume	Divide the dose by the concentration. For example, 1 mg ÷ 25 mg/mL = 0.04 mL
3. Convert to units	On a U-100 syringe, multiply the mL by 100. For example, 0.04 mL = 4 units
4. Check the syringe	Make sure the amount fits the syringe you are using
Worked example
Vial	50 mg GHK-Cu
Water	2 mL bacteriostatic water
Dose	1 mg
Syringe	100 units (1 mL)
Concentration	50 mg ÷ 2 mL = 25 mg/mL
Amount to draw	1 mg ÷ 25 mg/mL = 0.04 mL, which is 4 units on a U-100 syringe
Doses in the vial	50 mg ÷ 1 mg = 50 doses
Step-up schedule example
Vial	50 mg GHK-Cu mixed with 2 mL water = 25 mg/mL
Days 1–15	1 mg a day = 0.04 mL = 4 units (15 doses)
Days 16–30	2 mg a day = 0.08 mL = 8 units (15 more doses, 30 in total)
Total used	45 mg of the 50 mg vial (15 × 1 mg + 15 × 2 mg)
Disclaimer
This tool does math conversions only. It does not choose a dose for you or confirm product quality, safety, or medical suitability.

Reconstitution & Storage

Mixing a peptide takes about a minute. Keeping it good afterwards is the part most people get wrong, so follow the guide below and then store the vial the way we describe underneath it.

Step by step guide to reconstituting a peptide vial: bring vial and diluent to room temperature, draw the diluent, inject slowly down the inner wall, swirl gently, never shake

How to Reconstitute

Follow the five steps in the guide above. Bring the vial and the diluent to room temperature first, add the bacteriostatic water slowly down the inside wall so it does not foam and swirl gently until the powder is fully dissolved. Never shake the vial and never spray the bacteriostatic water straight onto the powder.

How to Store the Mixed Peptide

Once it is mixed, the vial goes back in the refrigerator at 2 to 8°C (35.6°F to 46.4°F) and stays there until you have used it. Write the mixing date on the vial so the clock is visible, not remembered.

Temperature: a normal fridge, 2 to 8°C (35.6°F to 46.4°F). Not the freezer, not a kitchen cupboard.
Shelf life: about 4 weeks. Past 28 days, discard it.
Light: keep it in the box or a dark drawer. Direct light degrades peptides.
Handling: swab the stopper before each draw, use a fresh needle and never shake the vial. Swirl gently if it needs mixing.
Freezing: do not freeze a mixed solution. Ice crystals and freeze-thaw cycles cut potency.
Dispose if: the liquid turns cloudy, changes colour, or shows visible particles.

Unmixed powder is far easier to store. Keep it dry, out of light, at room temperature for short periods or at -20°C for the long term and reconstitute only what you plan to use.

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